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XEOMIN vs BOTOX for Nonsurgical Wrinkle Relaxation

Spa Black is a plastic surgeon-owned San Antonio med spa backed by Dr. Thomas T. Jeneby, MD . Dr. Jeneby is a board-certified plastic surgeon with more than 20 years of experience in cosmetic and reconstructive plastic surgery. His background includes plastic surgery training through the University of Pennsylvania and certification from the American Board of Plastic Surgery. View Dr. Jeneby’s RealSelf profile.

Both XEOMIN® and BOTOX® are injectable “neuromodulators,” which means they can temporarily relax muscles. Consequently, wrinkles caused by muscular contractions are reduced or eradicated.

Both are most commonly used to treat facial wrinkles. They can also be used to treat non-cosmetic problems like migraines or excessive sweating.

Since BOTOX® and XEOMIN® operate by blocking nerve impulses, they are not recommended for people with neurological disorders. Women who are pregnant or nursing should also not use either

What is XEOMIN®?

XEOMIN® is a “naked” neuromodulator, which means it doesn’t have any additives. It therefore does not need to be refrigerated when being shipped, making it easier to store or transport than BOTOX® is. As a result, it can be less expensive than BOTOX®. The lack of additives also means that XEOMIN® is less likely to cause an allergic reaction.

XEOMIN® was cleared by the FDA to lessen the frown lines between the eyebrows. While some dermatologists do use it to treat other kinds of wrinkles, the FDA has not yet approved such uses. On the other hand, the FDA has approved using XEOMIN® to treat various conditions and some nerve disorders affecting the eye muscles.

When used to treat wrinkles, XEOMIN® generally produces results within a week, and those results can last for six months.

What is BOTOX®?

BOTOX® is also a neuromodulator. It also contains a protein that helps preserve it. This also means that it takes a bit longer than XEOMIN® to start showing results. As with XEOMIN®, those results also last for around six months.

Since BOTOX® has been around for much longer than XEOMIN® has, doctors and scientists have found more uses for it than they have for Xeomin. Like XEOMIN®, BOTOX® can be used to treat cervical dystonia and nerve disorders affecting the eye muscles. It can also be used to treat overactive bladder, migraines, excessive sweating, and stiff muscles in the elbows, wrists or fingers.

As a cosmetic, BOTOX® has been cleared by the FDA to treat more types of wrinkles than XEOMIN®. While XEOMIN® is designed to treat the frown lines between the brows, BOTOX® can also be used to treat forehead lines, crows’ feet, and lines around the neck.

How else do BOTOX® and XEOMIN® differ?

BOTOX® and XEOMIN® were developed and made by different companies. BOTOX® is produced by Allergan while XEOMIN® is made by Merz. BOTOX® is the oldest drug of its type and was approved by the FDA in 2002. XEOMIN® is much newer; it was approved by the FDA in 2010.

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